The 5G era of connectivity powered by intelligent edge and cloud networks will bring lightning fast bandwidth and ultra-low-latency performance as well as deep integration with cloud services. After years of anticipation, we are entering the implementation phase marked by initial rollouts of 5G networks around the world. Business leaders should now be identifying use cases that can harness these platforms to deliver positive business outcomes. Over the next few years, we expect that intelligent edge cloud networks will be a core driver of business transformation in several industries including manufacturing, retail, healthcare and transportation. Strategic planning is critical. Confidence in execution is crucial. Success will come to those organizations that harness the power of these technologies quickest and execute change programs to align strategies, people and processes accordingly. This Pathfinder paper is designed for business leaders who want to jump-start ideation, review common requirements and consider some practical recommendations.